Monica Whaley

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PCOS Update - Leptin

Posted on January 27, 2010 at 6:19 PM

As I’ve mentioned, my endocrinologist started me on Byetta about three months ago. I have since GAINED about 20lbs. ICK. I’m going to see her again on Monday, but she said I could stop taking it. I’m still taking the Metfomin; while I stopped losing after 35lbs, at least I wasn’t gaining anything more.


I was doing some research online about insulin resistance and found some information about leptin therapy. “It appears that, if one cannot make leptin, the brain thinks there is no fat and spurs the person on to eat more and more in a futile effort to get the leptin signal that fat is present” ( If that happens in addition to insulin resistance, sheesh! Not only does insulin resistance turn ALL food into fat, the brain may think that the body never has enough stored energy (fat) so you would keep eating all the time to build up that store to where the brain would be happy. No chance in H-E-double hockey sticks that you’d be able to lose anything. IF that’s going on with me, leptin therapy might be a possible solution. I plan on bringing it up with Dr. Rittenberry on Monday.

Categories: physical health

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